DeepMind published a complete human proteome data set online

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bozz4science Send message Joined: 2 May 20 Posts: 7 Credit: 228,784 RAC: 0	Message 102277 - Posted: 27 Jul 2021, 7:55:33 UTC Last modified: 27 Jul 2021, 7:55:51 UTC How about that? Google’s DeepMind puts human proteome online for free Quote: DeepMind partnered with the European Molecular Biology Laboratory (EMBL) to come up with the AlphaFold database, which predicts the three-dimensional structures of the human proteome – nearly all (98.5%) of the 20,000 or so proteins expressed by the human genome. AlphaFold has doubled the number of protein structures known to research, and that could help accelerate research into how diseases affect the body, and develop new medicines that can latch on to problem proteins effectively. It is one of the most significant contributions that AI has made to the advancement of science, according to its developers, although they acknowledge that some of the predictions will still need to be validated in experimental testing. Around a third of the structures are considered to be detailed and precise enough to allow drug design. ID: 102277 · Rating: 0 · rate: / Reply Quote

mikey Send message Joined: 5 Jan 06 Posts: 1895 Credit: 9,152,433 RAC: 4,296	Message 102278 - Posted: 27 Jul 2021, 11:31:22 UTC - in response to Message 102277. How about that? Google’s DeepMind puts human proteome online for free Quote: DeepMind partnered with the European Molecular Biology Laboratory (EMBL) to come up with the AlphaFold database, which predicts the three-dimensional structures of the human proteome – nearly all (98.5%) of the 20,000 or so proteins expressed by the human genome. AlphaFold has doubled the number of protein structures known to research, and that could help accelerate research into how diseases affect the body, and develop new medicines that can latch on to problem proteins effectively. It is one of the most significant contributions that AI has made to the advancement of science, according to its developers, although they acknowledge that some of the predictions will still need to be validated in experimental testing. Around a third of the structures are considered to be detailed and precise enough to allow drug design. WOO HOO!!!! Now hopefully the Rosetta folks can comb thru the 2 databases and see where we can advance the next part of the Science!! ID: 102278 · Rating: 0 · rate: / Reply Quote

[VENETO] boboviz Send message Joined: 1 Dec 05 Posts: 1994 Credit: 9,550,349 RAC: 6,340	Message 102310 - Posted: 30 Jul 2021, 7:00:12 UTC Interesting online course: "ColabFold - Making protein folding accessible to all via Google Colab!", using Alphafold2 and RoseTTAFold togheter. Here the link ID: 102310 · Rating: 0 · rate: / Reply Quote

[VENETO] boboviz Send message Joined: 1 Dec 05 Posts: 1994 Credit: 9,550,349 RAC: 6,340	Message 102311 - Posted: 30 Jul 2021, 7:08:25 UTC ColabFold is Alphafold2 (and RoseTTAFold)+ Google Colab + GPU ID: 102311 · Rating: 0 · rate: / Reply Quote

[VENETO] boboviz Send message Joined: 1 Dec 05 Posts: 1994 Credit: 9,550,349 RAC: 6,340	Message 108422 - Posted: 23 Jun 2023, 9:13:33 UTC A new version, with a lot of new features and improvements, of AlphaFold Protein Structure Database is online!! ID: 108422 · Rating: 0 · rate: / Reply Quote

DeepMind published a complete human proteome data set online - for free