CASP15: weeks 9 and 10 (June 27 - July 10)
For the next two weeks we have a similar plan for the target release. Both weeks will see four targets. On Mondays we will be releasing a large target (3000+ residues) for tertiary structure prediction, Tuesdays will be left blank, and Wednesdays through Fridays will see targets with the predictive accent in other modeling categories.

Such a schedule will allow not overloading tertiary structure prediction servers with too many tasks when the large target is in the works. In addition to this, we will allow extra time for predicting these targets (5 days for servers and 4 weeks for humans).

The other three targets from the first week are protein-Fab complexes intended for the assembly prediction (also CAPRI). We will not be collecting subunit predictions on these targets separately.

In the second week, the other three targets are for the assembly and ligand prediction. We will provide additional information on those in due time.

---

CASP15: week 11 (July 11-17)
Dear CASPers,

We are three weeks away from the end of the CASP15 target release season. After the last two weeks featuring very large structures (3000+ residues) and, as a result, a smaller number of targets, we are back to a more traditional target release schedule. Next week we will release 10 targets (two per day), including six targets for the assembly prediction. There will be no RNA and at the most one ligand prediction target.

---

CASP15: weeks 12 and 13 (July 18-31)
The last two weeks of CASP15 target release season will be packed with interesting targets. We will see large assembly complexes, protein-ligand complexes, targets with alternative conformations, and even a protein-RNA complex!

The first week (July 18-24) will start with a large heteromeric complex. Since this complex is big, we will allow extra time for both server and human prediction.

Tuesday will be free for tertiary/assembly prediction, but not for the ligand prediction. We will have a protein-ligand complex, where the structure of protein is known. The challenge would be to predict binding site and pose of the ligand. Additional information will be provided with the target release.

Wednesday will feature two more protein-ligand complexes.

On Thursday, we will have two RNA-protein complexes. The complexes represent alternative conformations corresponding to different particles in the same cryo-EM data set. The complexes contain one RNA molecule and several (4 or 6) protein molecules. Four targets will be released: T1189/R1189 pair for the A1(RNA):B6(prot) complex, and T1190/R1190 pair for the A1(RNA):B4(prot) complex. Predictions for each pair should be submitted in the same frame of reference so that concatenation of corresponding models for, say, T1189 and R1189 will give a coordinate set for the full RNA-protein complex.

The week will end with a long single-sequence target of ~1800 res.

Detailed plans for the last week of CASP will be published next Saturday. At this point we want to announce that we will have targets every day Monday through Friday, and that there will be no more RNA targets released.

---

July 30, end of target release
Yesterday we released the last prediction target in CASP15. All in all, we offered 127 targets in four prediction categories, including 94 targets for tertiary structure prediction, 47 targets for oligomeric prediction (more than 50% increase compared to CASP14), 12 targets for RNA prediction (including 2 RNA-protein complexes) and 23 targets for the ligand binding prediction.

In the next three weeks, we will continue collecting models for the already released targets, and also continue sending closed oligomeric targets for the estimation of model accuracy.

---

Only one week left to go in CASP15! In that week we will be collecting models on the remaining seven prediction targets.

After the prediction activity is over, we will start collecting methods descriptions for the CASP15 Abstract book. The abstracts will be collected from September 1 till September 15 and published electronically at the Prediction Center website. Detailed requirements for the preparation of abstracts will be published shortly, however you can start preparing your abstracts already now based on the templates from the previous CASPs. Those participating in CASP for the first time can check the CASP14 Abstract book at https://predictioncenter.org/casp14/doc/CASP14_Abstracts.pdf.

We are in the last stages of arranging the CASP15 conference (planning it in-person) and are hoping to open the registration in the next couple of weeks.

---

Program and abstracts of CASP15 Conference are published
Conference will start on December 10

---

A little surprise from CASP15: best RNA predictions are done WITHOUT AI/Deep Learning, but with "classical" methods.

---

Casp15 conference videos

---

Published results from CASP15

---