Keith Davies, project director and founder of Find-a-Drug, announced on 1 November 2005: Find-a-Drug to close on 16 December 2005.

The Find-a-Drug project has now processed more queries than the original 250 we envisaged. We have also targetted most of the recognised protein targets for the major project areas. Where we have been able to obtain experimental data to confirm biological activity, the predictions have exceeded our expectations. Smile Our experience suggests that it will be difficult to find collaborators who will be interested in the results of targetting proteins whose biological function is unknown or of little therapeutic interest.

We have concluded that there are insufficient worthwhile protein queries to continue the project into 2006 and have decided to close the project on 16 December 2005. Sad We will continue to make some new queries available over the coming weeks but will not accept results after the close of the project.

We are obviously very grateful for the contributions of members and will continue to work with our collaborators.
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PS I'm the guy in charge of Find-a-Drug
(This means I take all the blame and give all the credit to others)

There are thousands of us looking for a new home and several members are already running Rosetta@home. I am posting here because I didn't see a topic with posts by my old friends who have already joined this project.

Hello to new friends as well as fellow refugees.

(Where is the preview feature?)

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Hope you guys like Rosetta :) Seems to work well for me on various architectures and OS's and the feedback is very good..

Vester,

would a seperate forum for FAD refugees over at Free-DC be of any help? I'd be happy to set it up. Our main aim is to support the DC community.

Bok

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Free-DC

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...would a seperate forum for FAD refugees over at Free-DC be of any help? I'd be happy to set it up. Our main aim is to support the DC community.

Let's wait a little longer. The FaD forums are still open, numerous teams have message boards, and some of us are already posting at Free-DC.

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When Find-a-Drug closes, I'll be back with the unlocked AMD Athlon XP 2500+ and the AMD Athlon 2800+, but plan to do a few Marsenne primes with the Intel P4. (GIMPS has been optimized for Intel P4.)

How could I go wrong with David Baker and the University of Washington? I graduated with a B.S. Oceanography, UW '69. :-) I'm also a Lifetime Member of the UW Alumni Association. I'm so old that one of the Johnson brothers taught me Chemistry. (The Oceans by Johnson, Sverdrup, and Johnson)

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Hi peeps. Looking around atm.

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Keith Davies, project director and founder of Find-a-Drug, announced on 1 November 2005: Find-a-Drug to close on 16 December 2005.

The Find-a-Drug project has now processed more queries than the original 250 we envisaged. We have also targetted most of the recognised protein targets for the major project areas. Where we have been able to obtain experimental data to confirm biological activity, the predictions have exceeded our expectations. Smile Our experience suggests that it will be difficult to find collaborators who will be interested in the results of targetting proteins whose biological function is unknown or of little therapeutic interest.

We have concluded that there are insufficient worthwhile protein queries to continue the project into 2006 and have decided to close the project on 16 December 2005. Sad We will continue to make some new queries available over the coming weeks but will not accept results after the close of the project.

We are obviously very grateful for the contributions of members and will continue to work with our collaborators.
_________________
PS I'm the guy in charge of Find-a-Drug
(This means I take all the blame and give all the credit to others)

There are thousands of us looking for a new home and several members are already running Rosetta@home. I am posting here because I didn't see a topic with posts by my old friends who have already joined this project.

Hello to new friends as well as fellow refugees.

(Where is the preview feature?)

hey vester! i have it on 2 of my machines and still haven't gotten any work. are you doing any better?

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and if we are to find a home here, we have to talk them into changing this BB! :P :)

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Hi All,

I just posted the following on the Xtreme PC site on vavega's suggestion. how many FAD participants are there?







Dear FAD participants,

I was guided to this forum by the message below on the Rosetta@home science message boards--thank you vavega!!

My research group at the University of Washington is trying to solve the protein structure prediction problem. We have recently made a lot of progress and shown that the problem can very likely be solved given sufficient computing power, and we are extremely excited about the possibility of being able so solve the problem using distributed computing. We also work on designing new molecules, for example now we are hard at work trying to design an HIV vaccine. You can learn more about what we do by looking at the news articles at

https://boinc.bakerlab.org/rosetta/rah_articles.php

Because progress with this research is so limited by computing power, it would be fabulous if many of you would join our project. We give frequent feedback about the progress of the research, and try to involve participants as much as possible in the research, and we already have gotten a number of interesting ideas and suggestions back from participants. We will shortly be releasing the source code for people to explore on their own.

We've had our first server problems in the two months we've been on line in the last day or two, but these should be cleared up if not now then by tomorrow. Please join on!

Since I probably won't be checking these boards frequently, please post any questions on the rosetta@home message boards.

thank you,

David Baker


dear mr. baker,

i am one of the hordes of Fad members searching for a new distributed computing project to run once Fad shuts down dec. 16th. so far i have installed rosetta on 2 machines and haven't been able to download any work. i understand you're having problems with your server, but to those of us searching for a new project to support, this doesn't come off too well. to that end i would like to extend an invitation to you to come over to our home bulletin board and talk about your project. would you be willing? if so our address is

http://www.xtremepccentral.com/forums/index.php? if so please us this thread for your reply's.

http://www.xtremepccentral.com/foru...ead.php?t=21274

we are anxious to know if you can support a mass influx of new people and machines without the stoppages that we see right now.

thank you,

Di
vavega

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Thanks David!! It make a difference when the people from the project pop in like that. It belayed a lot of fears and shows us that your commited to helping.Most of us are standing around with a bewildered look wondering where to go from Fad.Bok and Py222 Have been helpful in pointing out some helpful hints to get this up and running.As have others from different forums.
I'm just one of about 70 people from XPC. If things go well as I'm hoping I'll put on about 50 dedicated systems.Mabee more as things proceed.
Bouncing around looking at the different boinc projects shows me that people have compiled the boinc program to fit the different projects.Has anybody done that here for Debian based linux,namely xandros??I'd appreciate any links to setting it up in linux.

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The Dutch Power Cows (DPC) haven't decided yet what they will do when FaD closes, but in the best spirit of the DPC, all members are free to join any project they choose. I for one am over to Rosetta. Keep an eye on DPC climbing in the team ranks ;)

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Well, so far I've got it running on 4 machines one of which only has 128Mb of ram as a tester as some members have concerns over ram usage...

Seems ok so far.

I quite like the sound of this project, the forum is workable, the members friendly, and David seems to be switched on to users demands, and with the personal appearance at XPC, it has helped with public relations etc...

I've set up a thread at XPC for questions/answers etc and to try and get more team support/testing.

Just one thing though, is this project likely to be a short term or long term project, and is it likely to be ran in stages. i.e. run flat out for a month or 2, then nothing until something else is processed and ready?...

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Regarding the future, look at the bottom of this page and you will see:

In the next several years, we aim to improve and extend our methods. We are particularly focused on improving the accuracy of high-resolution structure prediction (which will be required if the models are to be generally useful). To accomplish this, we will work to improve the underlying physical model and the sampling methodology. We are also developing improved methods to predict and redesign protein-DNA interaction specificity, and extending our protein design methodology to the design of enzymes that catalyze chemical reactions not catalyzed by naturally occurring proteins.

My bold.

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Huch....
All the big names are here... ;-)
No smilies?
So little Morphy has setup only 5 crunchers for Rosetta now and is looking for a solution to run some more with only one machine connected to the internet....

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Teddies....

...All the big names are here...

And the small ones!

How did you fix an avatar by the way?

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Well it's nice to see my bud's here.
Let's Rock.....:D

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Join Team XPC
http://www.xtremepccentral.com

Just one thing though, is this project likely to be a short term or long term project, and is it likely to be ran in stages. i.e. run flat out for a month or 2, then nothing until something else is processed and ready?...

the project is not intended to have wu's given out in intervals, they should flow constantly (if no system experience problems). as for a finishing date, unlike LHC where one (at least for sixtrack) is on the horizon, nothing came up here so far. guess even if we would solve the algorithms, we could start to model millions of proteins then...

Florian

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Florian
www.domplatz1.de

Avatar test. (Didn't work, did it? :))

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G'day everyone ,

Looks like I am looking for a new home too , I like this setup and will try to give it a go , Win2Kuser mentioned about a few expressing concerns about the minumum RAM , I have only 1 computer with 512mb, the other 3 have 256mb , so I will be following this with interest .

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My peak memory usage has been under 68 KB.

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